Safety and tolerability data for long-term use of fluconazole are scarce. Dr Davis and colleagues have published a study of 124 coccidioidomycosis patients in California and found that around half (52%) experienced significant side effects, in particular dry skin, hair loss and fatigue.
Rapid qPCR detection of a wide range of Coccidioides clinical specimens: has culture had its day?
An evaluation of a qPCR test for Coccidioides showed good sensitivity (74%) and specificity (100%), and produced results within 4 hours – outperforming fungal culture.